Maybe Kent or Norm can let us all know about the biophysiology behind the research that is now showing the effects that Seratonin has on sleep disordered breathing.
Oddly enough, seratonergic agents and precursors to seratonin such as L-tryptophan have been studied for more than 25 years as meds to HELP OSA. In fact, L-tryptophan was shown to decrease obstructive events AND increase REM back in 1983, but it’s been on and off the market several times for various reasons related to side effects.
Currently, several of the big boys in pharmaceuticals are working on seratonin ANTAGONISTS in the sleep aid market. So, there’s money to be found in them there pills…..